2019 Journal Articles

Pulse Shaped Dynamic Nuclear Polarization Under Magic Angle Spinning
A. Equbal, K. Tagami, and S. Han. ChemRxiv (2019)

Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms
M. Lin, N. K. Pandey, R. Barnes, S. Han, and R. Langen. Structure (2019)

Liquid-liquid phase separation and fibrillization of tau are independent processes with overlapping conditions
Y. Lin, Y. Fichou, Z. Zeng, N. Y. Hu, and S. Han. Biorxiv (2019)

Electron Spin Density Matching for Cross-Effect Dynamic Nuclear Polarization
Y. Li, A. Equbal, K. Tagami, and S. Han. Chem. Commun., 55 (2019), 7591-7594.

Protein shapes at the core of chronic traumatic encephalopathy
Y. Fichou and S. Han. Nature Struct. Mol. Biol., 26 (2019), 336-338.

Biradical rotamer states tune electron J coupling and MAS dynamic nuclear polarization enhancement
K. Tagami, A. Equbal, I. Kaminker, B. Kirtman, and S. Han Solid State Nucl. Mag. Res., 101 (2019), 12-20.

Proteorhodopsin Function is Primarily Mediated by Oligomerization in Different Micellar Surfactant Solutions
M. N. Idso, N. R. Baxter, S. Narayanan, E. Chang, J. M. Fisher, B. F. Chmelka, and S. Han J. Phys. Chem. B, 123 (19) (2019), 4180-4192.

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions
Y. Lin, J. McCarty, J. N. Rauch, K. T. Delaney, K. S. Kosik, G. H. Fredrickson, J.-E. Shea, S. Han. eLife, 8 (2019), e42571

Anomalous solute diffusivity in ionic liquids: Label-free visualization and physical origins
A. V. Bayles, C. S. Valentine, T. Überrück, S. P. O. Danielsen, S. Han, M. E. Helgeson, T. M. Squires. Phys. Rev. X, 9 (2018), 011048.

Cross-Effect Dynamic Nuclear Polarization Explained: Polarization, Depolarization, and Oversaturation
A. Equbal, A. Leavesley, S. K. Jain, S. Han. J. Phys. Chem. Lett., 10 (2019), 548-558.
Content of this publication inspired design of cover art of entailing journal issue.

2019 Book Chapter

Methods in Enzymology: Biological NMR Part B
Vol. 615, Elsevier Inc. (2019), 131-175.

Chapter Five - Overhauser Dynamic Nuclear Polarization for the Study of Hydration Dynamics, Explained
J. M. Franck and S. Han

2018 Journal Articles

Versatile Dynamic Nuclear Polarization Hardware with Integrated Electron Paramagnetic Resonance Capabilities
A. Leavesley, I. Kaminker, S. Han. eMagRes, 7 (2018), 133-154.
Included as part of the "Handbook of High Frequency Dynamic Nuclear Polarization NMR" series.

Cofactors are essential constituents of stable and seeding-active tau fibrils
Y. Fichou, Y. Lin, J. N. Rauch, M. Vigers, Z. Zeng, M. Srivastava, T. J. Keller, J. H. Freed, K. S. Kosik, S. Han. Proc. Nat. Acad. Sci., 115 (52) (2018), 13234-13239.
Highlighted in the UC Santa Barbara Current:

Effect of nitroxide spin probes on the transport properties of Nafion membranes
T. Überrück, O. Neudert, K.-D. Kreuer, B. Blümich, J. Granwehr, S. Stapf, S. Han. Phys. Chem. Chem. Phys., 20 (2018), 26660-26674.

Maximizing NMR signal per unit time by facilitating the e-e-n cross effect DNP rate
A. Leavesley, S. Jain, I. Kaminker, H. Zhang, S. Rajca, A. Rajca, S. Han. Phys. Chem. Chem. Phys. 20 (2018), 27646-27654. PMID: 30375593
Selected 2018 PCCP Hot Article

Tuning nuclear depolarization under MAS by electron T1e
A. Lund, A. Equibal, S. Han. Phys. Chem. Chem. Phys. 20 (2018), 23976-23987. PMID: 30211922. PMCID: PMC6208319
Selected 2018 PCCP Hot Article

Heterogeneity of network structure and water dynamics in ?-carrageenan gels probed by nanoparticle diffusometry
D. de Kort, E. Schuster, F. Hoeben, R. Barnes, M. Emondts, H. Janssen, N. Lorén, S. Han, H. van As, J. van Duynhoven. Langmuir, 34 (37) (2018), 11110-11120.

Multi-step phase-cycling in a free-electron laser-powered pulsed electron paramagnetic resonance spectrometer
C. B. Wilson, S. Aronson, J. A. Clayton, S. J. Glaser, S. Han, M. S. Sherwin. Phys. Chem. Chem. Phys., 20 (2018), 18097-18109.

Amplification of Dynamic Nuclear Polarization at 200 GHz by Arbitrary Pulse Shaping of the Electron Spin Saturation Profile
I. Kaminker, S. Han. J. Phys. Chem. Lett., 9 (11) (2018), 3110-3115.

Tuning conformation and properties of peptidomimetic backbones through dual N/C?-substitution
R. Kaminker, I. Kaminker, W. R. Gutekunst, Y. Luo, S. Lee, J. Niu, S. Han, C. J. Hawker. Chem. Comm., 54 (41) (2018), 5237-5240.

Truncated Cross Effect Dynamic Nuclear Polarization: An Overhauser Effect Doppelgänger
A. Equbal, Y. Li, A. Leavesley, S. Huang, S. Rajca, A. Rajca, S. Han, J. Phys. Chem. Lett., 9 (9) (2018), 2175-2180.

Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer’s disease filaments
Y. Fichou, M. Vigers, A. K. Goring, N. A. Eschmann, S. Han, Chem. Commun., 54 (36) (2018), 4573-4576.
PMID: 29664486

Quantitative analysis of zero-field splitting parameter distributions in Gd(III) complexes
J. A. Clayton, K. Keller, M. Qi, J. Wegner, V. Koch, H. Hintz, A. Godt, S. Han, G. Jeschke, M. S. Sherwin, M. Yulikov, Phys. Chem. Chem. Phys., 20 (15) (2018), 10470-10492. PMID: 29617015. PMCID: PMC6026474.

Functionally Active Membrane Proteins Incorporated in Mesostructured Silica Films
J. P. Jahnke, M. N. Idso, S. Hussain, M. J. N. Junk, J. M. Fisher, D. D. Phan, S. Han, B. F. Chmelka, J. Am. Chem. Soc., 140 (11) (2018), 3892-3906. PMID: 29533066.

Effect of Water/Glycerol Polymorphism on Dynamic Nuclear Polarization
A. Leavesley, C. B. Wilson, M. Sherwin, S. Han, Phys. Chem. Chem. Phys, 20 (15) (2018), 9897-9903.

Reversal of Paramagnetic Effects by Electron Spin Saturation
S. K. Jain, T. A. Siaw, A. Equbal, C. B. Wilson, I. Kaminker, S. Han, J. Phys. Chem. C, 122 (10) (2018), 5578-5589.

Surface Chemical Heterogeneity Modulates Silica Surface Hydration
A. M. Schrader, J. I. Monroe, R. Sheil, H. A. Dobbs, T. J. Keller, Y. Li, S. Jain, M. S. Shell, J. V. Israelachvili, S. Han, Proc. Natl. Acad. Sci. U.S.A., 115 (12) (2018) 2890-2895.
Highlighted in the UC Santa Barbara Current:

Perspective of Overhauser Dynamic Nuclear Polarization for the Study of Soft Materials
R. Barnes, S. Han, J. Biller, Curr. Opin. Colloid Interface Sci., 33(2018), 72-85.

2017 Journal Articles

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium
R. Barnes, S. Sun, Y. Fichou, F.W. Dahlquist, M. Heyden, S. Han, J. Am. Chem. Soc., 139 (49) (2017) 17890-17901.
Highlighted Cover Article:

Simple peptide coacervates adapted for rapid pressure-sensitive wet adhesion
I. Kaminker, W. Wei, A.M. Schrader, Y. Talmon, M.T. Valentine, J.N. Israelachvili, J.H. Waite, S. Han, Soft Matter., 13 (48) (2017) 9122-9131.

Universal Dynamics of Molecular Reorientation in Hybrid Lead Iodide Perovskites
D.H Fabini, T.A. Siaw, C.C. Stoumpos, G. Laurita, D. Olds, K. Page, J.G. Hu, M.G. Kanatzidis, S. Han, R. Seshadri, J. Am. Chem. Soc., 139 (46) (2017) 16875-16884.
Highlighted Cover Article:

Conformation-based assay of tau protein aggregation
Y. Fichou, N.A. Eschmann, T.J. Keller, S. Han, Methods Cell Biol., 141 (2017) 89-112.

Proton-based structural analysis of heptahelical transmembrane protein in lipid bilayers
D. Lalli, M.N. Idso, L.B. Andreas, S. Hussain, N. Baxter, S. Han, B. Chmelka, G. Pintacuda, J. Am. Chem. Soc., 139 (37) (2017) 13006-13012. PMID: 28724288. PMCID: PMC5741281.
Highlighted Cover Article:

Water Dynamics from the Surface to the Interior of a Supramolecular Nanostructure
J.H. Ortony, B. Qiao, C.J. Newcomb, T.J. Keller, L.C. Palmer, E. Deiss-Yehiely, M.O. Cruz S. Han, S.I. Stupp, J. Am. Chem. Soc., 139 (26) (2017) 8915–8921
Highlighted in Nature Chemistry News and Views:

RNA Stores Tau Reversibly in Complex Coacervates
X. Zhang, N.E. Eschmann, Y. Lin, H. Zhou, J. Rauch, I. Hernandez, E. Guzman, K.S. Kosik, S. Han, PLOS Biol., 15 (7) (2017) e2002183. PMID: 28683104. PMCID: PMC5500003
Also published in bioRxiv:
Highlighted in:

Arbitrary waveform modulated pulse EPR at 200 GHz
I. Kaminker, R. Barnes, S. Han, J. Magn. Reson., 279 (2017) 81-90 PMID: 28482216. PMCID: PMC5519772

Signature of an aggregation-prone conformation of tau
N.A. Eschmann, E.R. Georgieva, P. Ganguly, P.P. Borbat, M.D. Rappaport, Y. Akdogan, J.H. Freed, J.E. Shea, S. Han, Sci. Rep., 7 (2017) 1-10 PMID: 28303942. PMCID: PMC5356194

Gd3+-Gd3+ distances exceeding 3 nm determined by very high frequency continuous wave electron paramagnetic resonance
J.A. Clayton, M. Qi, A. Godt, D. Goldfarb, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 19 (7) (2017)5127-5136 PMID: 28139788. PMCID: PMC5394103

Effect of electron spectral diffusion on static dynamic nuclear polarization at 7 Tesla
A. Leavesley, D. Shimon, T. Siaw, A. Feintuch, D. Goldfarb, S. Vega, I. Kaminker, S. Han, Phys. Chem. Chem. Phys., 19 (5)(2017) 3596-3605. PMID: 28094364