2020 Journal Articles

Trigonal Bipyramidal V3+ Complex as an Optically Addressable Molecular Qubit Candidate
M. S. Fataftah, S. L. Bayliss, D. W. Laorenza, X. Wang, B. T. Phelan, C. B. Wilson, P. J. Mintun, B. D. Kovos, M. R. Wasielewski, S. Han, M. S. Sherwin, D. D. Awschalom, and D. E. Freedman. J. Am. Chem. Soc., 142(48) (2020), 20400-20408

Liquid-liquid phase separation of tau driven by hydrophobic interaction facilitates fibrillization of tau
Y. Lin, Y. Fichou, A. P. Longhini, L. C. Llanes, P. Yin, G. C. Bazan, K. S. Kosik, S. Han J. Mol. Biol. (2020)

Dynamic Nuclear Polarization with Vanadium(IV) Metal Centers
S. K. Jain, C.-J. Yu, C. B. Wilson, T. Tabassum, D. E. Freedman, and S. Han. Chem (2020)
Also published in ChemRxiv.
Featured in The UCSB Current,, and ScienceDaily.

End-to-End Distance Probability Distributions of Dilute Poly(ethylene oxide) in Aqueous Solution
N. Sherck, T. Webber, D. R. Brown, T. Keller, M. Barry, A. DeStefano, S. Jiao, R. A. Segalman, G. H. Fredrickson, M. S. Shell, and S. Han J. Am. Chem. Soc., 11 (2020).
Spotlighted on Recent JACS Publications.

1H Thermal Mixing Dynamic Nuclear Polarization with BDPA as Polarizing Agents
Y. Li, A. Equbal, T. Tabassum., and S. Han J. Phys. Chem. Lett., 11 (2020), 9195-9202
Live Slide Talk can be found here.

The proline-rich domain promotes Tau liquid–liquid phase separation in cells
X. Zhang, M. Vigers, J. McCarty, J. N. Rauch, G. H. Fredrickson, M. Z. Wilson, J.-E. Shea, S. Han, and K. S. Kosik J. Cell Biol., 219 (11) (2020), e202006054

Dehydration entropy drives liquid-liquid phase separation by molecular crowding
S. Park, R. Barnes, Y. Lin, B.-J. Jeon, S. Najafi, K. T. Delaney, G. H. Fredrickson, J.-E. Shea, D. S. Hwang, and S. Han Comm. Chem., 3 (83) (2020)

Balancing Dipolar and Exchange coupling in Biradicals to Maximize Cross Effect Dynamic Nuclear Polarization
A. Equbal, K. Tagami, and S. Han Phys. Chem. Chem. Phys., 22 (2020), 13569-13579.

Crossover from a Solid Effect to Thermal Mixing 1H Dynamic Nuclear Polarization with Trityl-OX063
A. Equbal, Y. Li, T. Tabassum, and S. Han J. Phys. Chem. Lett., 11 (9) (2020), 3718–3723.
Live Slides Talk can be found here.

Tuning molecular adsorption in SBA-15-type periodic mesoporous organosilicas by systematic variation of their surface polarity
H. Moon, S. Han, and S. Scott. Chem. Sci., 11 (2020), 3702-3712

Mechanisms of heparin-induced tau aggregation revealed by single nanopore
N. Giamblanco, Y. Fichou, J.-M. Janot, E. Balanzat, S. Han, and S. Balme. ACS Sens., 5 (4) (2020), 1158–1167.

The Role of Backbone Polarity on Aggregation and Conduction of Ions in Polymer Electrolytes
N. S. Schauser, D. J. Grzetic, T. Tabassum, G. A. Kliegle, M. L. Le, E. M. Susca, S. Antoine, T. J. Keller, K. T. Delaney, S. Han, R. Seshadri, G. H. Fredrickson, R. A. Segalman J. Am. Chem. Soc., 142 (15) (2020), 7055-7065

Water Structure and Properties at Hydrophilic and Hydrophobic Surfaces
J. Monroe, M. Barry, A. DeStefano, P. A. Gorturk, S. Jiao, D. Robinson-Brown, T. Webber, E. J. Crumlin, S. Han, and S. Shell. Annu. Rev. Chem. Biomol. Eng., 11 (2020), 523-557.

Electrostatic Environment of Proteorhodopsin Affects the pKa of Its Buried Primary Proton Acceptor
C.-T. Han, J. Song, T. Chan, C. Pruett, and S. Han. Biophys. J., 118 (8) (2020), 1838-1849.

Electrostatically driven complex coacervation and amyloid aggregation of tau are independent processes with overlapping conditions.
Y. Lin, Y. Fichou, Z. Zeng, N. Y. Hu, and S. Han. ACS Chem. Neurosci., 11 (4) (2020), 615–627.
Also published in BioRxiv:

Phosphonate‐Modified UiO‐66 Brønsted Acid Catalyst and Its Use in Dehydra‐Decyclization of 2‐Methyltetrahydrofuran to Pentadienes
M. D. de Mello, G. Kumar, T. Tabassum, S. K. Jain, T.-H. Chen, S. Caratzoulas, X. Li, D. G. Vlachos, S. Han, S. L. Scott, P. Dauenhauer, and M. Tsapatsis. Angew. Chem., 59 (2020), 2-9.

2020 Book Chapter

Tau Condensates
K. Kosik, S. Han Kumar,. Adv. Exp. Med. Biol., 1184 (2020), 327-339.

2019 Journal Articles

Tau-cofactor complexes as building blocks of tau fibrils
Y. Fichou, Z. R. Oberholtzer, H. Ngo, C.-Y. Cheng, T. J. Keller, N. A. Eschmann, and S. Han. Front. Neurosci., 13 (2019), 1339.

Pulse Shaped Dynamic Nuclear Polarization Under Magic Angle Spinning
A. Equbal, K. Tagami, and S. Han. J. Phys. Chem. Lett., 10 (2019), 7781-7788.
Also published in ChemRxiv:
Live Video Presentation on the topic can be found here.

Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms
M. Lin, N. K. Pandey, R. Barnes, S. Han, and R. Langen. Structure, 27 (10) (2019), 1570-1580.e4.

Electron Spin Density Matching for Cross-Effect Dynamic Nuclear Polarization
Y. Li, A. Equbal, K. Tagami, and S. Han. Chem. Commun., 55 (2019), 7591-7594.

Protein shapes at the core of chronic traumatic encephalopathy
Y. Fichou and S. Han. Nature Struct. Mol. Biol., 26 (2019), 336-338.

Biradical rotamer states tune electron J coupling and MAS dynamic nuclear polarization enhancement
K. Tagami, A. Equbal, I. Kaminker, B. Kirtman, and S. Han Solid State Nucl. Mag. Res., 101 (2019), 12-20.

Proteorhodopsin Function is Primarily Mediated by Oligomerization in Different Micellar Surfactant Solutions
M. N. Idso, N. R. Baxter, S. Narayanan, E. Chang, J. M. Fisher, B. F. Chmelka, and S. Han J. Phys. Chem. B, 123 (19) (2019), 4180-4192.

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions
Y. Lin, J. McCarty, J. N. Rauch, K. T. Delaney, K. S. Kosik, G. H. Fredrickson, J.-E. Shea, S. Han. eLife, 8 (2019), e42571

Anomalous solute diffusivity in ionic liquids: Label-free visualization and physical origins
A. V. Bayles, C. S. Valentine, T. Überrück, S. P. O. Danielsen, S. Han, M. E. Helgeson, T. M. Squires. Phys. Rev. X, 9 (2018), 011048.

Cross-Effect Dynamic Nuclear Polarization Explained: Polarization, Depolarization, and Oversaturation
A. Equbal, A. Leavesley, S. K. Jain, S. Han. J. Phys. Chem. Lett., 10 (2019), 548-558.
Content of this publication inspired design of cover art of entailing journal issue.

2019 Book Chapter

Methods in Enzymology: Biological NMR Part B
Vol. 615, Elsevier Inc. (2019), 131-175.

Chapter Five - Overhauser Dynamic Nuclear Polarization for the Study of Hydration Dynamics, Explained
J. M. Franck and S. Han

2018 Journal Articles

Versatile Dynamic Nuclear Polarization Hardware with Integrated Electron Paramagnetic Resonance Capabilities
A. Leavesley, I. Kaminker, S. Han. eMagRes, 7 (2018), 133-154.
Included as part of the "Handbook of High Frequency Dynamic Nuclear Polarization NMR" series.

Cofactors are essential constituents of stable and seeding-active tau fibrils
Y. Fichou, Y. Lin, J. N. Rauch, M. Vigers, Z. Zeng, M. Srivastava, T. J. Keller, J. H. Freed, K. S. Kosik, S. Han. Proc. Nat. Acad. Sci., 115 (52) (2018), 13234-13239.
Highlighted in the UC Santa Barbara Current:

Effect of nitroxide spin probes on the transport properties of Nafion membranes
T. Überrück, O. Neudert, K.-D. Kreuer, B. Blümich, J. Granwehr, S. Stapf, S. Han. Phys. Chem. Chem. Phys., 20 (2018), 26660-26674.

Maximizing NMR signal per unit time by facilitating the e-e-n cross effect DNP rate
A. Leavesley, S. Jain, I. Kaminker, H. Zhang, S. Rajca, A. Rajca, S. Han. Phys. Chem. Chem. Phys. 20 (2018), 27646-27654. PMID: 30375593. PMCID: PMC6370975. NIHMSID: NIHMS995519.
Selected 2018 PCCP Hot Article

Tuning nuclear depolarization under MAS by electron T1e
A. Lund, A. Equbal, S. Han. Phys. Chem. Chem. Phys. 20 (2018), 23976-23987. PMID: 30211922. PMCID: PMC6208319. NIHMSID: NIHMS989193
Selected 2018 PCCP Hot Article

Heterogeneity of network structure and water dynamics in ?-carrageenan gels probed by nanoparticle diffusometry
D. de Kort, E. Schuster, F. Hoeben, R. Barnes, M. Emondts, H. Janssen, N. Lorén, S. Han, H. van As, J. van Duynhoven. Langmuir, 34 (37) (2018), 11110-11120.

Multi-step phase-cycling in a free-electron laser-powered pulsed electron paramagnetic resonance spectrometer
C. B. Wilson, S. Aronson, J. A. Clayton, S. J. Glaser, S. Han, M. S. Sherwin. Phys. Chem. Chem. Phys., 20 (2018), 18097-18109.

Amplification of Dynamic Nuclear Polarization at 200 GHz by Arbitrary Pulse Shaping of the Electron Spin Saturation Profile
I. Kaminker, S. Han. J. Phys. Chem. Lett., 9 (11) (2018), 3110-3115.

Tuning conformation and properties of peptidomimetic backbones through dual N/C?-substitution
R. Kaminker, I. Kaminker, W. R. Gutekunst, Y. Luo, S. Lee, J. Niu, S. Han, C. J. Hawker. Chem. Comm., 54 (41) (2018), 5237-5240.

Truncated Cross Effect Dynamic Nuclear Polarization: An Overhauser Effect Doppelgänger
A. Equbal, Y. Li, A. Leavesley, S. Huang, S. Rajca, A. Rajca, S. Han, J. Phys. Chem. Lett., 9 (9) (2018), 2175-2180.

Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer’s disease filaments
Y. Fichou, M. Vigers, A. K. Goring, N. A. Eschmann, S. Han, Chem. Commun., 54 (36) (2018), 4573-4576.
PMID: 29664486

Quantitative analysis of zero-field splitting parameter distributions in Gd(III) complexes
J. A. Clayton, K. Keller, M. Qi, J. Wegner, V. Koch, H. Hintz, A. Godt, S. Han, G. Jeschke, M. S. Sherwin, M. Yulikov, Phys. Chem. Chem. Phys., 20 (15) (2018), 10470-10492. PMID: 29617015. PMCID: PMC6026474.

Functionally Active Membrane Proteins Incorporated in Mesostructured Silica Films
J. P. Jahnke, M. N. Idso, S. Hussain, M. J. N. Junk, J. M. Fisher, D. D. Phan, S. Han, B. F. Chmelka, J. Am. Chem. Soc., 140 (11) (2018), 3892-3906. PMID: 29533066.

Effect of Water/Glycerol Polymorphism on Dynamic Nuclear Polarization
A. Leavesley, C. B. Wilson, M. Sherwin, S. Han, Phys. Chem. Chem. Phys, 20 (15) (2018), 9897-9903.

Reversal of Paramagnetic Effects by Electron Spin Saturation
S. K. Jain, T. A. Siaw, A. Equbal, C. B. Wilson, I. Kaminker, S. Han, J. Phys. Chem. C, 122 (10) (2018), 5578-5589.

Surface Chemical Heterogeneity Modulates Silica Surface Hydration
A. M. Schrader, J. I. Monroe, R. Sheil, H. A. Dobbs, T. J. Keller, Y. Li, S. Jain, M. S. Shell, J. V. Israelachvili, S. Han, Proc. Natl. Acad. Sci. U.S.A., 115 (12) (2018) 2890-2895.
Highlighted in the UC Santa Barbara Current:

Perspective of Overhauser Dynamic Nuclear Polarization for the Study of Soft Materials
R. Barnes, S. Han, J. Biller, Curr. Opin. Colloid Interface Sci., 33(2018), 72-85.

2017 Journal Articles

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium
R. Barnes, S. Sun, Y. Fichou, F.W. Dahlquist, M. Heyden, S. Han, J. Am. Chem. Soc., 139 (49) (2017) 17890-17901.
Highlighted Cover Article:

Simple peptide coacervates adapted for rapid pressure-sensitive wet adhesion
I. Kaminker, W. Wei, A.M. Schrader, Y. Talmon, M.T. Valentine, J.N. Israelachvili, J.H. Waite, S. Han, Soft Matter., 13 (48) (2017) 9122-9131.

Universal Dynamics of Molecular Reorientation in Hybrid Lead Iodide Perovskites
D.H Fabini, T.A. Siaw, C.C. Stoumpos, G. Laurita, D. Olds, K. Page, J.G. Hu, M.G. Kanatzidis, S. Han, R. Seshadri, J. Am. Chem. Soc., 139 (46) (2017) 16875-16884.
Highlighted Cover Article:

Conformation-based assay of tau protein aggregation
Y. Fichou, N.A. Eschmann, T.J. Keller, S. Han, Methods Cell Biol., 141 (2017) 89-112.

Proton-based structural analysis of heptahelical transmembrane protein in lipid bilayers
D. Lalli, M.N. Idso, L.B. Andreas, S. Hussain, N. Baxter, S. Han, B. Chmelka, G. Pintacuda, J. Am. Chem. Soc., 139 (37) (2017) 13006-13012. PMID: 28724288. PMCID: PMC5741281.
Highlighted Cover Article:

Water Dynamics from the Surface to the Interior of a Supramolecular Nanostructure
J.H. Ortony, B. Qiao, C.J. Newcomb, T.J. Keller, L.C. Palmer, E. Deiss-Yehiely, M.O. Cruz S. Han, S.I. Stupp, J. Am. Chem. Soc., 139 (26) (2017) 8915–8921
Highlighted in Nature Chemistry News and Views:

RNA Stores Tau Reversibly in Complex Coacervates
X. Zhang, N.E. Eschmann, Y. Lin, H. Zhou, J. Rauch, I. Hernandez, E. Guzman, K.S. Kosik, S. Han, PLOS Biol., 15 (7) (2017) e2002183. PMID: 28683104. PMCID: PMC5500003
Also published in bioRxiv:
Highlighted in:

Arbitrary waveform modulated pulse EPR at 200 GHz
I. Kaminker, R. Barnes, S. Han, J. Magn. Reson., 279 (2017) 81-90 PMID: 28482216. PMCID: PMC5519772

Signature of an aggregation-prone conformation of tau
N.A. Eschmann, E.R. Georgieva, P. Ganguly, P.P. Borbat, M.D. Rappaport, Y. Akdogan, J.H. Freed, J.E. Shea, S. Han, Sci. Rep., 7 (2017) 1-10 PMID: 28303942. PMCID: PMC5356194

Gd3+-Gd3+ distances exceeding 3 nm determined by very high frequency continuous wave electron paramagnetic resonance
J.A. Clayton, M. Qi, A. Godt, D. Goldfarb, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 19 (7) (2017) 5127-5136 PMID: 28139788. PMCID: PMC5394103

Effect of electron spectral diffusion on static dynamic nuclear polarization at 7 Tesla
A. Leavesley, D. Shimon, T. Siaw, A. Feintuch, D. Goldfarb, S. Vega, I. Kaminker, S. Han, Phys. Chem. Chem. Phys., 19 (5) (2017) 3596-3605. PMID: 28094364

2016 Journal Articles

Hydration dynamics of a peripheral membrane protein
O. Fisette, C. Paslack, R. Barnes, J.M. Isas, R. Langen, M. Heyden, S. Han, L.V. Schafer, J. Am Chem. Soc., 138 (2016) 11526-11535 PMID: 27548572; PMCID: PMC5519773.

Adenosine A2a receptors form distinct oligomers in protein detergent complexes
N.S. Schonenbach, M.D. Rieth, S. Han, M.A. O'Malley, FEBS Lett., 590 (2016) 3295–3306 PMID: 27543907; PMCID: PMC5039092.

Contrasting Effects of Glycerol and DMSO on Lipid Membrane Surface Hydration Dynamics and Forces
A. Schrader, C. Cheng, J. Israelachvili, S. Han, J. Chem. Phys., 145 (2016) 041101 PMID: 27475340; PMCID: PMC4967073.

Molecular and structural basis of low interfacial energy of complex coacervates in water
Y. Jho, H. Yoo, Y. Lin, S. Han, D. Hwang, Adv. Colloid Interface Sci., 239 (2017) 61–73 PMID: 27499328.

Biocontinuous Fluid Structure with Low Cohesive Energy: Molecular Basis for Exceptionally Low Interfacial Tension of Complex Coacervate Fluids
K. Huang, H. Yoo, Y. Jho, S. Han, D. Hwang, ACS Nano, 10 (2016) 5051-5062

Stability of protein-specific hydration shell on crowding
K. Huang, C.N. Kingsley, R. Sheil, C. Cheng, J.B. Bierma, K.W. Roskamp, D. Khago, R.W. Martin, S. Han, J. Am. Chem. Soc., 138 (16) (2016) 5392–5402 PMID: 27052457.

A versatile and modular quasi optics-based 200 GHz dual dynamic nuclear polarization and electron paramagnetic resonance instrument
T.A. Siaw, A. Leavesley, A. Lund, I. Kaminker, S. Han, J. Magn. Reson., 264 (2016) 131-153 PMCID: PMC4770585.

Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau
A. Pavlova, C. Cheng, M. Kinnebrew, J. Lew, F. Dahlquist, S. Han, Proc. Natl. Acad. Sci., 113 (2) (2016) E127-E136 PMCID: PMC4720316

2015 Journal Articles

Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?
P. Stals, C. Cheng, L. Beek, A. Wauters, A. Palmans, S. Han, E. Meijer, Chem. Sci., 7 (2015) 2011-2015

Tau Aggregation Propensity Engrained in Its Solution State
N. Eschmann, T. Do, N. LaPointe, J. Shea, S. Feinstein, M. Bowers, S. Han, J. Phys. Chem., 119 (45) (2015) 14421–14432 PMID: 26484390; PMCID: PMC4645975

Mussel Coating Protein-Derived Complex Coacervates Mitigate Frictional Surface Damage
D. Miller, S. Das, K. Huang, S. Han, J. Israelachvili, J. Waite, ACS Biomater. Sci. Eng., 1 (11) (2015) 1121–1128 PMID: 26618194; PMCID: PMC4642218
ACS Editors' Choice Paper

Direct Dynamic Nuclear Polarization Targeting Catalytically Active 27Al Sites
A. Lund, M. Hsieh, T. Siaw, S. Han, Phys. Chem. Chem. Phys., 17 (2015) 25449-25454 PMID: 26365719

Anomalously rapid hydration water diffusion dynamics near DNA surfaces
J. Franck, Y. Ding, K. Stone, P. Qin, S. Han, J. Am. Chem. Soc., 137 (37) (2015) 12013-12023 10.1021/jacs.5b05813 PMID: 26256693; PMCID: PMC4656248

Correlating steric-hydration forces with water dynamics through surface force and diffusion NMR measurements in a lipid-DMSO-H2O system
A. Schrader, S. Donaldson, J. Song, C. Cheng, D. Lee, S. Han, J. Israelachvili, Proc. Natl. Acad. Sci., 112 (34) (2015) 10708–10713 PMID: 26261313; PMCID: PMC4553805

Active Cancellation - A Means to Zero Dead-Time Pulse EPR
J. Franck, R. Barnes, T. Keller, T. Kaufmann, S. Han, J. Magn. Reson., 261 (2015) 199-204 PMID: 26507308; PMCID: PMC4688155

DMSO induces dehydration near lipid membrane surfaces
C. Cheng, J. Song, J. Pas, L. Meijer, S. Han, Biophys. J., 109 (2) (2015) 330-339 PMID: 26200868; PMCID: PMC4621616

Ion specific effects: decoupling ion-ion and ion-water interactions
J. Song, M. Kim, T. Kang, S. Han, Phys. Chem. Chem. Phys., 17 (2015) 8306-8322 PMID: 25761273; PMCID: PMC4656249

Functional Consequences of the Oligomeric Assembly of Proteorhodopsin
S. Hussain, M. Kinnebrew, N. Schonenbach, E. Aye, S. Han, J. Molec. Biol., 427 (6B) (2015) 1278-1290 PMID: 25597999; PMCID: PMC4374980

Nanometer-Scale Water and Proton Diffusion Heterogeneities across Water Channels in Polymer Electrolyte Membranes
J. Song, O. H. Han,  S. Han, Angew. Chem., 54 (12) (2015) 3615-3620 PMID: 25630609; PMCID: PMC4450673

2015 Book Chapters

Methods in Enzymology: Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions - Part B
Edited by: P. Z. Qin, K. Warncke

Vol. 564, Elsevier Inc. (2015)
Overhauser Dynamic Nuclear Polarization Studies on Local Water Dynamics
I. Kaminker, R. Barnes, and S. Han PMID: 26477261

Protein NMR - Modern Techniques and Biomedical Applications
Edited by: Lawrence Berliner

Vol. 32, Springer (2015) 43-74
Mapping Out Protein Hydration Dynamics by Overhauser Dynamic Nuclear Polarization
C. Cheng, J. Song, J. Franck, S. Han

2014 Journal Articles

Local water diffusivity as a molecular probe of surface hydrophilicity 
J. Song, B. Allison, S. Han, MRS Bull., 39 (12) (2014) 1082-1088

Cholesterol Enhances Surface Water Diffusion of Phospholipid Bilayers
C. Y. Cheng, L. Olijve, R. Kausik, S. Han, J. Chem. Phys., 141 (22D513) (2014) PMID: 25494784; PMCID: PMC4201661

Determining the oligomeric structure of proteorhodopsin by Gd3+-based pulsed dipolar spectroscopy of multiple distances
D.T. Edwards, T. Huber, S. Hussain, K.M. Stone, M. Kinnebrew, I. Kaminker, E. Matalon, M.S. Sherwin, D. Goldfarb, S. Han, Structure, 22 (11) (2014) 1677-1686 PMID: 25438671.

Intrinsic Surface-Drying Properties of Bioadhesive Proteins
Y. Akdogan, W. Wei, K. Huang, Y. Kageyama, E. W. Danner, D. R. Miller, N. R. Martinez Rodriguez, J. H. Waite, S. Han, Angew. Chem., 126 (42) (2014) 11435-11438 PMID: 25168789; PMCID: PMC4198389
Featured in Nature Materials | Research Highlights

Role of Electron Spin Dynamics on Solid-State Dynamic Nuclear Polarization Performance
T. Siaw, M. Fehr, A. Lund, A. Latimer, S. Walker D. Edwards, S. Han, Phys. Chem. Chem. Phys., 16 (2014) 18694-18706. PMID: 24968276.

Probing water density and dynamics in the chaperonin GroEL cavity
J. Franck, M. Sokolovski, N. Kessler, E. Matalon, M. Gordon-Grossman, S. Han, D. Goldfarb, A. Horovitz, J. Am. Chem. Soc., 136 (26) (2014) 9396-9403 PMID: 24888581; PMCID: PMC4091268

Specific Ions Modulate Diffusion Dynamics of Hydration Water on Lipid Membrane Surfaces
J. Song, J. Franck, P. Pincus, M.W. Kim, S. Han, J. Am. Chem. Soc., 136 (6) (2014) 2642-2649 PMID: 24456096; PMCID: PMC3985948

2013 Journal Articles

Fluidity and Water in Nanoscale Domains Define Coacervate Hydrogels
J.H. Ortony, S.H. Choi, J.M. Spruell, J.N. Hunt, N.A. Lynd, D.V. Krogstad, V.S. Urban, C.J. Hawker, E.J. Kramer, S. Han, Chemical Sciences 5 (2013) 58-67

Hydration Dynamics as an Intrinsic Ruler for Refining Protein Structure at Lipid Membrane Interfaces
C.Y. Cheng, J. Varkey, M.R. Ambroso, R. Langen, S. Han, Proc. Natl. Acad. Sci. 110 (42) (2013) 16838–16843 PMID: 24082088; PMCID: PMC3800990

DAC-board based X-band EPR Spectrometer with Arbitrary Waveform Control (w/Audio Slide Presentation)
T. Kaufmann, T.J. Keller, J.M. Franck, R.P. Barnes, S.J. Glaser, J.M. Martinis, S. Han, J. Magn. Reson. 235 (2013) 95-108 PMID: 23999530; PMCID: PMC3863685

Quantitative cw Overhauser Dynamic Nuclear Polarization for the Analysis of Local Water Dynamics
J. M. Franck, A. Pavlova, J.A. Scott, S. Han, Prog. Nucl. Magn. Reson. 74 (2013) 33-56 PMID: 24083461; PMCID: PMC3798041

Temperature Dependence of High Field 13C Dynamic Nuclear Polarization Processes below 35 Kelvin
S.A. Walker, D.T. Edwards, T. Siaw, B.D. Armstrong, S. Han, Phys. Chem. Chem. Phys. 15 (36) (2013) 15106-15120 PMID: 23925724.

Extending the Distance Range Accessed with Continuous Wave EPR with Gd3+ Spin Probes at High Magnetic Fields
D.T. Edwards, Z. Ma, T.J. Meade, D. Goldfarb, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 15 (2013) 11313-11326 PMID: 23732863; PMCID: PMC4142211

Overhauser Dynamic Nuclear Polarization-Enhanced NMR Relaxometry
J.M. Franck, R. Kausik, S. Han, Microporous and Mesoporous Materials, 178 (2013) 113-118 PMID: 23837010; PMCID: PMC3702190

Asymmetric Collapse in Biomimetic Complex Coacervates Revealed by Local Polymer and Water Dynamics
J.H. Ortony, D.S. Hwang, J.M. Franck, J.H. Waite, S. Han, Biomacromolecules, 14(5) (2013) 1395-1402 PMID: 23540713; PMCID: PMC4090114

Phase Cycling with a 240 GHz Free Electron Laser-powered Electron Paramagnetic Resonance Spectrometer
D.T. Edwards, Y. Zhang, S.J. Glaser, S. Han, M.S. Sherwin, Phys. Chem. Chem. Phys., 15 (2013) 5707-5719 PMID: 23474874.

Nonlinear Scaling of Surface Water Diffusion with Bulk Water Viscosity of Crowded Solutions
J.M. Franck, J.A. Scott, S. Han, J. Am. Chem. Soc., 135(11) (2013) 4175-4178 PMID: 23347324; PMCID: PMC3785640.

Structural Insight into Proteorhodopsin Oligomers
K. M. Stone, J. Voska, M. Kinnebrew, A. Pavlova, M. J. N. Junk, S. Han, Biophys. J., 104(2) (2013) 472-481 PMID: 23442869; PMCID: PMC3552253

Dynamic Nuclear Polarization Methods in Solids and Solutions to Explore Membrane Proteins and Membrane Systems
C.Y. Cheng and S. Han, Annu. Rev. Phys. Chem., 64 (2013) 507-532 PMID: 23331309.

Transmembrane Protein Activation Refined by Site-Specific Hydration Dynamics
S. Hussain, J. M. Franck, S. Han, Angew. Chem. Int. Ed., 52(7) (2013) 1953-1958 PMID: 23307344

2013 Journal Articles

Annual Review of Physical Chemistry
Vol. 64, Annual Reviews (2013)
Dynamic Nuclear Polarization Methods in Solids and Solutions to Explore Membrane Proteins and Membrane Systems
C. Cheng and S. Han PMID: 23331309

2012 Journal Articles

Quantitative Analysis of Molecular Transport across Liposomal Bilayer by J-mediated 13C Dynamic Nuclear Polarization
C.Y. Cheng, J.G.M.O. Goor, S. Han, Anal. Chem., 84(21) (2012) 3936-3940 PMID: 23072518; PMC4656247.

Nature of Interactions between PEO-PPO-PEO Triblock Copolymers and Lipid Membranes: The Role of Hydration Dynamics Revealed by Dynamic Nuclear Polarization
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, Biomacromolecules, 13(9) (2012) 2624-2633 PMID: 22808941.

Distance measurements across randomly distributed nitroxide probes from the temperature dependence of the electron spin phase memory time at 240 GHz
D.T. Edwards, S. Takahashi, M. S. Sherwin, S. Han, J. Magn. Reson., 223 (2012) 198-206 PMID: 22975249.

Inductively coupled NMR probe for versatile dynamic nuclear polarization operation at 7 Tesla: observation of 61 ± 2% 1H polarization at 4 K
T. Siaw, S. A. Walker, B. D. Armstrong, S. Han, J. Magn. Reson., 221 (2012) 5-10 PMID: 22743536.

Hyperpolarized Water as an MRI Contrast Agent
M. D. Lingwood, T. Siaw, N. Sailasuta, O. A. Abulseoud, H. R. Chan, B. D. Ross, P. Bhattacharya, S. Han, , Radiology, 265 (3) (2012) 418-425 10.1148/radiol.1211180 PMID: 22996746; PMCID: PMC3480810.

Pulsed electron paramagnetic resonance spectroscopy powered by a free-electron laser
S. Takahashi, L.-C. Brunel, D. T. Edwards, J. van Tol, G. Ramian, S. Han, M. S. Sherwin, Nature 489 (74160) (2012)409-13 PMID: 22996555.

Overhauser dynamic nuclear polarization amplification of NMR flow imaging
M. D. Lingwood, A. J. Sederman, M. D. Mantle, L. F. Gladden, S. Han, J. Magn. Reson. 216 (2012) 94–100

An ultrasensitive tool exploiting hydration dynamics to decipher weak lipid membrane–polymer interactions
C. Cheng, J. Wang, R. Kausik, K. C. Lee, S. Han, J. Magn. Reson. 215 (2012) 115-119 PMID: 22230738.

2011 Journal Articles

Site-Specific Hydration Dynamics in the Nonpolar Core of a Molten Globule by Dynamic Nuclear Polarization of Water
B.D. Armstrong, J. Choi, C. Lopez, D. A. Wesener, W. Hubbell, S. Cavagnero, S. Han, J. Am. Chem. Soc.133 (2011) 5987–5995 PMID: 21443207; PMCID: PMC3095581

Dynamics and State of Lipid Bilayer-internal Water Unraveled with Solution State 1H Dynamic Nuclear Polarization
R. Kausik, S. Han, Phys. Chem. Chem. Phys. (2011) 13, 7732-7746 PMID: 21423982.

Probing the Hydration Water Diffusion of Macromolecular Surfaces and Interfaces
J. H. Ortony, C.-Y. Cheng, R. Kausik, A. Pavlova, J. Hunt, S. Han, New J. Phys.13 (2011) 015006 (15pp)

2011 Book Chapters

Annual Reports on NMR Spectroscopy
Edited by: Graham A. Webb

Vol. 73, Elsevier Academic Press (2011)
Solution State Dynamics Nuclear Polarization 
M. D. Lingwood, S. Han. (Pages 83-126) PMID: 12137529

2007–2010 Journal Articles

A 200 GHz Dynamic Nuclear Polarization Spectrometer
B.D. Armstrong, D.T. Edwards, R.J. Wylde, S.A. Walker, S. Han, Phys. Chem. Chem. Phys., 12 (2010) 5920-5926 PMID: 20461268.

Continuous Flow Overhauser Dynamic Nuclear Polarization of Water in the Fringe Field of a Clinical Magnetic Resonance Imaging System for Authentic Image Contrast
M. D. Lingwood, T. A. Siaw, N. Sailasuta, B. D. Ross, P. Bhattacharya and S. Han, J. Magn. Reson. 205 (2) (2010) 247-254 PMID: 20541445; PMCID: PMC4724375.

Heisenberg Spin Exchange Effects of Nitroxide Radicals on Overhauser Dynamic Nuclear Polarization in the Low Field Limit at 1.5 mT
M.D. Lingwood, I.A. Ivanov, A.R. Cote, S. Han, J. Magn. Reson. 204 (1) (2010) 56-63 PMID: 20188611.

L-band Overhauser dynamic nuclear polarization
S. Garcia, J.H. Walton, B.A. Armstrong, S. Han, M.J. Mcarthy, J. Magn. Reson. 203 (1) (2010) 138-143 PMID: 20045658.

Ultrasensitive Detection of Interfacial Water Diffusion on Lipid Vesicle Surfaces at Molecular Length Scales
R. Kausik, S. Han.
J. Am. Chem. Soc. 131 (51) (2009) 18254-18256 PMID: 19791740.

Dynamic Nuclear Polarization of 13C in Aqueous Solutions under Ambient Conditions
M.D. Lingwood, S. Han, J. Magn. Reson. 201 (2) (2009) 137-145 PMID: 19783462.

Local Water Dynamics in Coacervated Polyelectrolytes Monitored through Dynamic Nuclear Polarization-Enhanced 1H NMR
R. Kausik, A. Srivastava, P.A. Korevaar, G. Stucky, J.H. Waite, S. Han, Macromolecules 42 (19) (2009) 7404–7412 PMID: 20814445; PMCID: PMC2929756

Site-specific Dynamic Nuclear Polarization of Hydration Water as a Generally Applicable Approach to Monitor Protein Aggregation
A. Pavlova, E.R. McCarney, D.W. Peterson, F.W. Dahlquist, J. Lew, S. Han, Phys. Chem. Chem. Phys. (PCCP) 11 (2009) 6833-6839 PMID: 19639158; PMCID: PMC3153360

Overhauser Dynamic Nuclear Polarization and Molecular Dynamics Simulations using Pyrroline and Piperidine Ring Nitroxide Radicals
B.D. Armstrong, P. Soto, J. Shea, S. Han, J. Magn. Reson. 200 (2009) 137-141 PMID: 19535275.

Overhauser Dynamic Nuclear Polarization To Study Local Water Dynamics
B.D. Armstrong, S. Han, J. Am. Chem. Soc. 131 (13) (2009) 4641-4647 PMID: 19290661.

Study of Local Diffusion Coefficients of the Hydration Layer of Lipid Vesicle Bilayers
R. Kausik, B. D. Armstrong, S. Han, Diffusion Fundamentals 10 (2009) 27.1-27.4 PMCID: PMC3985948

Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance and Electron Spin Resonance Studies of Hydration and Local Water Dynamics in Micelle and Vesicle Assemblies
E. R. McCarney, B.D. Armstrong, R. Kausik, S. Han, Langmuir. 24 (18) (2008) 10062-10072 PMID: 18700788.

Dynamic Nuclear Polarization Studies of Local Water Dynamics in Soft Molecular Assemblies at 9.8 GHz 
S. Han, E. R. McCarney, B.D. Armstrong, Appl. Magn. Reson. 34 (3-4) (2008) 439-451

Portable X-Band System for Solution State Dynamic Nuclear Polarization
B.D. Armstrong, M.D. Lingwood, E.R. McCarney, E.R. Brown, P. Blümler, S. Han, J. Magn. Reson. 191 (2) (2008)273-281 PMID:18226943.

Spin-Labeled Gel for the Production of Radical-Free Dynamic Nuclear Polarization Enhanced Molecules for NMR Spectroscopy and Imaging
E.R. McCarney, S. Han, J. Magn. Reson. 190 (2) (2008) 307-315

Local Hydration Dynamics in Soft Matter by Dynamic Nuclear Polarization of 1H-water
B. D. Armstrong, R. Kausik, S. Han, AIP Conf. Proc. 1081 (2008) 14-17

A New Model for Overhauser Enhanced Nuclear Magnetic Resonance Using Nitroxide Radicals
B. D. Armstrong, S. Han, J. Chem. Phys. 127 (10) (2007) 104508-10.

Hyperpolarized Water as an Authentic Magnetic Resonance Imaging Contrast Agent
E.R. McCarney, B. D. Armstrong, M. D. Lingwood, S. Han, Proc. Nat. Acad. Sci. USA. 104 (6) (2007) 1754-1759.

para-Hydrogen-Induced Polarization in Heterogeneous Hydrogenation Reactions
I.V. Koptyug, K.V. Kovtunov, S.R. Burt, M.S. Anwar, C. Hilty, S. Han, A. Pines, R.Z. Sagdeev, J. Am. Chem. Soc.129 (17) (2007) 5580-5586

2007–2010 Book Chapters

Magnetic Resonance Microscopy
Edited by: S. Codd, J. Seymour
Wiley-VCH, Weinheim, Germany
Dynamic Nuclear Polarization-Enhanced Magnetic Resonance Analysis at X-band using Amplified 1H Water Signal 
S. Han., E.R. McCarney, B.D. Armstrong and M.D. Lingwood (Chapter 11)

Nuclear Magnetic Resonance Imaging
S. Stapf, S. Han
Ullmann Encyclopedia Article, Wiley-VCH, Germany, 2007

2000–2006 Journal Articles

Sensitivity Enhancement by Exchange Mediated Magnetization Transfer of the Xenon Biosensor Signal
S. Garcia, L. Chavez, T.J. Lowery, S. Han, D.E. Wemmer, A. Pines, J. Magn. Reson. 184 (2006) 72-77.

Auxiliary Probe Design Adaptable to Existing Probes for Remote Detection NMR, MRI, and Time-of-Flight Tracing
S. Han, J. Granwehr, S. Garcia, E. McDonnell, A. Pines, J. Magn. Reson. 182 (2006) 260-272.

SQUID-detected Microtesla MRI in the Presence of Metal
M. Mößle, S. Han, W. R. Myers, S. Lee, N. Kelso, M. Hatridge, A. Pines, J. Clarke, J. Magn. Reson. 179 (2006) 146-151.

NMR velocity mapping of gas flow around solid objects
S. Han, K. Pierce, A. Pines, Phys. Rev. E 74 (2006) 016302.

Improved NMR Based Bio-Sensing with Optimized Delivery of Polarized 129Xe to Solutions
S. Han, S. Garcia, T. J. Lowery, E. J. Ruiz, J.A. Seeley, L. Chavez, D. S. King, D. E. Wemmer, A. Pines, Anal. Chem. 77 (2005) 4008-4012.

NMR Analysis on Microfluidic Devices by Remote Detection
E. McDonnell, S. Han, C. Hilty, K. L. Pierce, A. Pines, Anal. Chem. 77 (24) (2005) 8109-8114.

Time-of-flight flow imaging using NMR Remote Detection
J. Granwehr, E. Harel, S. Han, S. Garcia, L. Chavez, A. Pines, Phys. Rev. Lett. 95 (2005) 075503.

Microfluidic Gas Flow Profiling Using Hyperpolarized Xenon and Remote Detection
C. Hilty, E. McDonnell, J. Granwehr, K. Pierce, S. Han, A. Pines, Proc. Nat. Acad. Sci. 102 (2005) 14960-14963.

Time Resolved Spectroscopic NMR Imaging Using Hyperpolarized 129-Xe
S. Han, H. Kühn, F. W. Häsing, K. Münnemann, B. Blümich, S. Appelt. J. Magn. Reson. 167 (2004) 298-305.

Imaging of a Mixture of Hyperpolarized He3 and Xe129
R.H. Acosta, P. Blümler, S. Han, S. Appelt, W. Häsing, J. Schmiedeskamp, W. Heil, H.W. Reson. Imag. 22 (2004) 1077-1083.

Proton Magnetic Resonance Imaging of Diffusion of High- and Low-Molecular-Weight Contrast Agents in Opaque Porous Media Saturated with Water
T. Osuga, S. Han. Magn. Reson. Imag. 22 (7) (2004) 1039-1042.

Three-Dimensional Phase-encoded Chemical Shift MRI in the Presence of Inhomogeneous Fields
V. Demas, D. Sakellariou, C. Meriles, S. Han, J. Reimer, A. Pines. Proc. Nat. Acad. Sci. 101 (24) (2004) 8845-8847.

Remotely-detected high-field MRI of Porous Samples
A. Seeley, S. Han, A. Pines. J. Magn. Reson. 167, 282-290 (2004).

Time Resolved Spectroscopic NMR Imaging Using Hyperpolarized 129-Xe
S. Han, H. Kühn, F. W. Häsing, K. Münnemann, B. Blümich, S. Appelt. J. Magn. Reson. 167, 298-305 (2004).

Remote Amplification of NMR Signal
A. J. Moule, M. Spence, S.-I Han, J.A. Seeley, K. Pierce, S. Saxena, A. Pines. Proc. Nat. Acad. Sci. 100 (16) (2003) 9122-9127.

Spectrally Resolved Velocity Exchange Spectroscopy of Two-Phase Flow
A. A. Khrapitchev, S.-I Han, S. Stapf, B. Blümich. J. Magn. Reson. 159, 36-45 (2002).

In Situ Observation of Diffusion and Reaction Dynamics in Gel Microreactors by Chemically Resolved NMR Microscopy
M. Küppers, C. Heine, S. Han, S. Stapf, B. Blümich. Appl. Magn. Reson. 22, 235-246 (2002).

Spatio-Temporal Correlations in Transport Processes Determined by Multi-PFG Experiments
S. Stapf, S. Han, C. Heine, B. Blümich. Concepts in Magn. Reson. 14 (3), 172-211 (2002).

NMR Imaging of Falling Drops
S. Han, S. Stapf, B. Blümich. Phys. Rev. Lett. 87 (14), 144501-144504 (2001).

Rheology of Blood by NMR
S. Han, O. Marseille, C. Gehlen, B. Blümich. J. Magn. Reson. 152 (2001) 87-94.

One-shot velocimetry using Echo Planar Imaging Microscopy
S. Han, P. T. Callaghan. J. Magn. Reson. 148 (2001) 349-354.

Two-Dimensional PFG-NMR for Encoding Correlations of Position, Velocity and Acceleration in Fluid Transport.
S. Han, S. Stapf, B. Blümich. J. Magn. Reson. 146, 169-180 (2000).

NMR Characterization of the Pore Structure and of Anisotropic Self-Diffusion in Salt Water Ice
M. I. Menzel, S. Han, S.Stapf, B. Blümich. J. Magn. Reson. 143, 376-381 (2000).

Two-Dimensional Representation of Position, Velocity and Acceleration by PFG-NMR
S. Han, B. Blümich. Appl. Magn. Reson. 18, 101-114 (2000).

2000–2006 Books and Book Chapters

Magnetic Resonance Imaging in Chemical Engineering
S. Stapf and S. Han.
Wiley-VCH, Weinheim, Germany (2006).

Fluid Flow and Trans-membrane Exchange in a Hemodialyzer Module
S. Han, S. Stapf.
in: S. Stapf, S. Han (Eds.) "NMR Imaging in Chemical Engineering" Wiley-VCH, Weinheim, Germany.

Broadening the application range of NMR and MRI by remote detection
S. Han, J. Granwehr, C. Hilty.
in: S. Stapf, S. Han (Eds.) "NMR Imaging in Chemical Engineering" Wiley-VCH, Weinheim, Germany.

2000–2006 Patents

Polarization Matrix for Producing Radical-Free Nuclear Spin Hyperpolarized Molecules as Contrast Agents.
S. Han, E.R. McCarney, B. D. Armstrong, M. D. Lingwood.
Provisional Patent (2006)

Remote NMR/MRI Detection of Laser Polarized Gases
Alex Pines, Sunil Saxena, Adam Moule, Megan Spence, Juliette Seeley, Kimberly Pierce, Song-I Han, Josef Grahnwehr
CIP U.S. Patent Application, IB-1771PCT, filed Oct. 9, 2002.